a tool for identifying drug-targetable redox-active disulphides

Lysozyme C-2

Intramolecular

Cysteine 83 and cysteine 99

A redox-regulated disulphide may form within Lysozyme C-2 between cysteines 83 and 99 (65 and 81 respectively in this structure).

Details

Redox score ?

84

PDB code

Structure name

solution structure of mouse lysozyme m

Structure deposition date

2002-03-27

Thiol separation (Å)

2

Half-sphere exposure sum ?

74

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

83

Residue number B

99

Peptide name

Lysozyme C-2

Ligandability

Cysteine 83 of Lysozyme C-2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 99 of Lysozyme C-2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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